1. Gene
  2. ESRRB - estrogen-related receptor beta Gene

ESRRB - estrogen-related receptor beta Gene

中文名称:雌激素相关受体 β

种属: Rattus norvegicus

同用名: Err2; Errb

基因 ID: 299210 | 基因类型: protein coding

关于 ESRRB

Primary_assembly 6: 106,008,095-106,160,791 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 264 orthologues, 8 paralogues and is associated with 6 phenotypes. Biased expression in Kidney (RPKM 39.9), Heart (RPKM 38.6) and 3 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动 DNA 结合转录因子活性,RNA 聚合酶 II 特异性; RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性;和 RNA 聚合酶 II 复合物结合活性。参与糖原生物合成过程的正向调节和糖酵解过程的正向调节。预测位于浓缩染色体;胞质溶胶;和核质。预测为集成器复合体的一部分。该基因的人类直向同源基因与常染色体隐性遗传性非综合征性耳聋 35 相关。与人类 ESRRB(雌激素相关受体 β)直向同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in positive regulation of glycogen biosynthetic process and positive regulation of glycolytic process. Predicted to be located in condensed chromosome; cytosol; and nucleoplasm. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

ESRRB 基因产物(1)

mRNA Protein Name
NM_001008516.3 NP_001008516.3 steroid hormone receptor ERR2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of glycogen biosynthetic process IDA
IDA: 通过直接分析推断
24481529 RGD
involved in positive regulation of glycolytic process IDA
IDA: 通过直接分析推断
24481529 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ESRRB 蛋白结构

NR_DBD_ERR

NR_DBD_ERR: cd07170 (174 - 269)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (288 - 507)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 510 a.a.
蛋白主名 其他名称

steroid hormone receptor ERR2

ERR-beta

estrogen receptor-like 2

nuclear receptor subfamily 3 group B member 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ESRRB NCBI NCBI:2103