1. Gene
  2. Nuak1 - NUAK family kinase 1 Gene

Nuak1 - NUAK family kinase 1 Gene

中文名称:NUAK 家族激酶 1

种属: Rattus norvegicus

同用名: RGD1309956

基因 ID: 299694 | 基因类型: protein coding

关于 Nuak1

Primary_assembly 7: 19,329,933-19,401,913 forward strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 257 orthologues, 26 paralogues and is associated with 2 phenotypes. Biased expression in Lung (RPKM 126.), Heart (RPKM 112.2) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动 p53 结合活性和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程,包括细胞对葡萄糖饥饿的反应;细胞衰老的调节;和肌球蛋白轻链磷酸酶活性的调节。预计位于纤维中心;微管细胞骨架;和核质。预计在细胞质中有活性。与人类 NUAK1(NUAK 家族激酶 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to glucose starvation; regulation of cellular senescence; and regulation of myosin-light-chain-phosphatase activity. Predicted to be located in fibrillar center; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human NUAK1 (NUAK family kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nuak1 基因产物(1)

mRNA Protein Name
NM_001106774.1 NP_001100244.1 NUAK family SNF1-like kinase 1

Nuak1 蛋白结构

STKc_NUAK

STKc_NUAK: cd14073 (53 - 306)

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  • 661 a.a.
蛋白主名 其他名称

NUAK family SNF1-like kinase 1

AMPK-related protein kinase 5

NUAK family, SNF1-like kinase, 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nuak1 NCBI NCBI:9891