2. Gene
  3. DRAXIN - dorsal inhibitory axon guidance protein Gene

DRAXIN - dorsal inhibitory axon guidance protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：背侧抑制性轴突导向蛋白

种属: Homo sapiens

同用名: UNQ3119; neucrin; AGPA3119; C1orf187

基因 ID: 374946 | 基因类型: protein coding

关于 DRAXIN

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,686,635-11,725,857 (from NCBI)

This gene has 1 transcript (splice variant) and 198 orthologues. Low expression observed in reference dataset.

功能概要

预计参与经典 Wnt 信号通路的负调控；神经元投射发育的负调节；和神经系统发育。预计在轴突延伸的负调节和神经元凋亡过程的负调节的上游或内部起作用。预计在细胞外区域活跃。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in negative regulation of canonical Wnt signaling pathway; negative regulation of neuron projection development; and nervous system development. Predicted to act upstream of or within negative regulation of axon extension and negative regulation of neuron apoptotic process. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

DRAXIN 基因产物(1)

mRNA Protein Name
NM_198545.4 NP_940947.3 draxin precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity EXP
EXP: 通过实验结果推断
29503192 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26190107 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DRAXIN 蛋白结构

Draxin

Draxin: Draxin (35 - 349)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
蛋白主名 其他名称

draxin

dorsal repulsive axon guidance protein

重组 DRAXIN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76878 Draxin Protein, Human (HEK293, His) Q8NBI3 (G26-V349) ≥95%

关联疾病

疾病名称 别名
Third Cranial Nerve Disease

Disorder Of Oculomotor Nerve

Oculomotor Nerve Disorder

Oculomotor Nerve Paralysis

Third Cranial Nerve Disorder
Mirror Movements 1

Congenital Mirror Movement Disorder

Bimanual Synergia

Congenital Mirror Movements

Familial Congenital Controlateral Synkinesia

Familial Congenital Mirror Movements

Hereditary Congenital Controlateral Synkinesia

Hereditary Congenital Mirror Movements

Isolated Congenital Controlateral Synkinesia

Isolated Congenital Mirror Movements

Mirror Movements

MRMV1

Mirror Movements 1 And/Or Agenesis Of The Corpus Callosum

Mirror Movements, Congenital

Bimanual Synkinesis

Cmm

Mirror Movements, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03990 DRAXIN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus DRAXIN MGD MGI:1917683
Macaca mulatta DRAXIN VGNC VGNC:106352
Bos taurus DRAXIN VGNC VGNC:28204
Rattus norvegicus DRAXIN RGD RGD:1585098
Canis familiaris DRAXIN VGNC VGNC:40090
Felis catus DRAXIN VGNC VGNC:61622
Others DRAXIN NCBI
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