MMP16 - matrix metallopeptidase 16 Gene

中文名称：基质金属肽酶 16

种属: Homo sapiens

同用名: MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP

关于 MMP16

功能概要

基质金属蛋白酶 (MMP) 家族的蛋白质参与正常生理过程 (如胚胎发育、繁殖和组织重塑) 以及疾病过程 (如关节炎和转移) 中细胞外基质的分解。大多数 MMP's 被分泌为无活性的前蛋白，当被细胞外蛋白酶切割时被激活。编码的蛋白质通过切割激活 MMP2。该基因曾被称为 MT-MMP2，后改名为 MT-MMP3 或 MMP16。[RefSeq 提供，2010 年 10 月]

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]