2. Gene
  3. CDK16 - cyclin dependent kinase 16 Gene

CDK16 - cyclin dependent kinase 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶 16

种属: Homo sapiens

同用名: PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE

基因 ID: 5127 | 基因类型: protein coding

关于 CDK16

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:47,218,303-47,229,997 (from NCBI)

This gene has 22 transcripts (splice variants), 174 orthologues, 26 paralogues and is associated with 1 phenotype. Ubiquitous expression in heart (RPKM 14.6), brain (RPKM 14.2) and 25 other tissues.

功能概要

该基因编码的蛋白质属于蛋白激酶 ser/thr 家族的 cdc2/cdkx 亚家族。它可能在终末分化细胞的信号转导级联中发挥作用；在胞吐作用中；以及从内质网运输分泌物。该基因被认为可以逃避 X 失活。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2009 年 12 月]

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]

CDK16 基因产物(15)

mRNA Protein Name
XM_047442152.1 XP_047298108.1 cyclin-dependent kinase 16 isoform X5
NM_006201.5 NP_006192.1 cyclin-dependent kinase 16 isoform 1
XM_011543922.2 XP_011542224.1 cyclin-dependent kinase 16 isoform X4
XM_011543926.2 XP_011542228.1 cyclin-dependent kinase 16 isoform X7
NM_001170460.2 NP_001163931.1 cyclin-dependent kinase 16 isoform 3
NM_033018.4 NP_148978.2 cyclin-dependent kinase 16 isoform 2
XM_011543920.4 XP_011542222.1 cyclin-dependent kinase 16 isoform X1
XM_011543923.3 XP_011542225.1 cyclin-dependent kinase 16 isoform X6
XM_011543925.3 XP_011542227.1 cyclin-dependent kinase 16 isoform X7
NM_033019.1
XM_047442153.1 XP_047298109.1 cyclin-dependent kinase 16 isoform X8
XM_017029569.2 XP_016885058.1 cyclin-dependent kinase 16 isoform X3
XM_011543924.3 XP_011542226.1 cyclin-dependent kinase 16 isoform X7
XM_047442154.1 XP_047298110.1 cyclin-dependent kinase 16 isoform X9
XM_011543921.2 XP_011542223.1 cyclin-dependent kinase 16 isoform X2

CDK16 蛋白结构

Pkinase

Pkinase: Protein kinase domain (166 - 446)

  • 0
  • 100
  • 200
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  • 400
  • 496 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 16

PCTAIRE-motif protein kinase 1

cell division protein kinase 16

serine/threonine-protein kinase PCTAIRE-1

testis secretory sperm-binding protein Li 224n

重组 CDK16 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76536 PCTAIRE1 Protein, Human (sf9, GST) Q00536-1 (M1-F496) ≥95%

关联疾病

疾病名称 别名
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-X0150 JSH-150 Inhibitor 98.36% 否
HY-148062 RSS0680 98.03% 否
HY-148063 DB0614 98.80% 否
HY-X0009A JSH-009 dimaleate Inhibitor / 否
HY-160213 JA397 Inhibitor / 否
HY-146680 FLT3/ITD-IN-4 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CDK16 RGD RGD:620584
Felis catus CDK16 VGNC VGNC:68735
Mus musculus CDK16 MGD MGI:97516
Bos taurus CDK16 VGNC VGNC:27119
Macaca mulatta CDK16 VGNC VGNC:71160
Canis familiaris CDK16 VGNC VGNC:39048
Others CDK16 NCBI
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