2. Protein Tyrosine Kinase/RTK Cell Cycle/DNA Damage MAPK/ERK Pathway
  3. FLT3 RET CDK MAP4K
  4. FLT3/ITD-IN-4

FLT3/ITD-IN-4 (Compound 16) 是一种选择性的 FLT3 内部串联重复突变 (FLT3-ITD) 抑制剂，IC50 值为 2.3 nM。FLT3/ITD-IN-4 可用于急性骨髓性白血病的研究。

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FLT3/ITD-IN-4 Chemical Structure

FLT3/ITD-IN-4 Chemical Structure

CAS No. : 2278278-04-7

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FLT3/ITD-IN-4 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with an IC50 of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research[1].

IC50 & Target

CDK16/Cyclin Y

1768 nM (EC50)

MAP4K4

5737 nM (EC50)

FLT3-ITD

2.3 nM (IC50)

FLT3 D835Y

4.84 nM (IC50)

RET

277 nM (EC50)

FLT3

443 nM (EC50)

ZAK/MLTK

1069 nM (EC50)

DDR2

2494 nM (EC50)

EPHA7

3255 nM (EC50)

NTRK1

3857 nM (EC50)

分子量

458.47

Formula

C25H22N4O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FLT3/ITD-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FLT3/ITD-IN-42278278-04-7FLT3RETCDKMAP4KCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3Cyclin dependent kinaseMAPK Kinase Kinase Kinasetyrosine kinase inhibitoracute myeloid leukemiaMV4- 11EOL-1MOLM-13MONO-MAC-1MONO-MAC-6Inhibitorinhibitorinhibit

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目录号：
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