2. Gene
  3. PPIC - peptidylprolyl isomerase C Gene

PPIC - peptidylprolyl isomerase C Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肽基脯氨酰异构酶 C

种属: Homo sapiens

同用名: CYPC

基因 ID: 5480 | 基因类型: protein coding

关于 PPIC

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:123,023,250-123,036,725 (from NCBI)

This gene has 2 transcripts (splice variants), 199 orthologues and 22 paralogues. Ubiquitous expression in thyroid (RPKM 32.1), placenta (RPKM 29.0) and 24 other tissues.

功能概要

该基因编码的蛋白质是肽基-脯氨酰顺反异构酶 (PPIase) ) 家族的成员。 PPIases 催化寡肽中脯氨酸亚胺肽键的顺反异构化，加速蛋白质的折叠。与其他 PPIase 类似，这种蛋白质可以结合免疫抑制剂环孢菌素 A。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

PPIC 基因产物(1)

mRNA Protein Name
NM_000943.5 NP_000934.1 peptidyl-prolyl cis-trans isomerase C precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidyl-prolyl cis-trans isomerase activity IDA
IDA: 通过直接分析推断
20676357 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PPIC 蛋白结构

Pro_isomerase

Pro_isomerase: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD (43 - 195)

  • 0
  • 100
  • 200
  • 212 a.a.
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase C

PPIase C

重组 PPIC 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71223 PPIC Protein, Human (Trx-His) P45877 (K31-D182) ≥95%

关联疾病

疾病名称 别名
Disseminated Intravascular Coagulation

Defibrination Syndrome

Dic

Diffuse Or Disseminated Intravascular Coagulation

Fibrinolytic Purpura

Consumption Coagulopathy

Diffuse Intravascular Coagulation

Dic - [Disseminated Intravascular Coagulation]

Disseminated Intravascular Coagulopathy

Fibrinolysis Nos

Thrombolytic Purpura
Fish Allergy

Allergy To Fish
Crab Allergy

Green Mud Crab Allergy

Scylla Paramamosain Allergy
Post-Cardiac Arrest Syndrome

Post Cardiac Syndrome
Thrombotic Thrombocytopenic Purpura

Purpura, Thrombotic Thrombocytopenic

Ttp

Thrombotic Thrombocytopenic Purpura, Acquired

Idiopathic Thrombotic Thrombocytopenic Purpura

Moschcowitz Disease

Moschcowitz'S Syndrome

Moschowitz Syndrome

Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Familial Thrombotic Thrombocytopenia Purpura

Moschkowitz Disease

Purpura Thrombotic Thrombocytopenic

Familial Thrombotic Thrombocytopenic Purpura

Microangiopathic Hemolytic Anemia

Congenital Thrombotic Thrombocytopenic Purpura

Autoimmune Thrombotic Thrombocytopenic Purpura

Ttp - [Thrombotic Thrombocytopenic Purpura]

Moschcowitz Syndrome
Chicken Egg Allergy

Gallus Gallus Egg Allergy
Apple Allergy

Malus Domestica Fruit Allergy
Alkhurma Hemorrhagic Fever

Alkhumra Haemorrhagic Fever
Melon Allergy

Cucumis Melo Fruit Allergy
Peach Allergy

Prunus Persica Fruit Allergy
Vegetable Allergy
Kyasanur Forest Disease

Kfd

Monkey Fever

Kfd Virus

Kyasanur Hemorrhagic Fever

Monkey Disease

Monkey Diseases

Kfd - [ Kyasanur Forest Disease]

Monkey Sickness
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10948 PPIC Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PPIC RGD RGD:1303221
Mus musculus PPIC MGD MGI:97751
Canis familiaris PPIC VGNC VGNC:44850
Felis catus PPIC VGNC VGNC:97562
Bos taurus PPIC VGNC VGNC:33196
Macaca mulatta PPIC VGNC VGNC:81508
Others PPIC NCBI
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