1. Gene
  2. AZGP1 - alpha-2-glycoprotein 1, zinc-binding Gene

AZGP1 - alpha-2-glycoprotein 1, zinc-binding Gene

中文名称:α-2-糖蛋白 1,锌结合

种属: Homo sapiens

同用名: ZAG; ZA2G

基因 ID: 563 | 基因类型: protein coding

关于 AZGP1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:99,966,730-99,976,031 (from NCBI)

This gene has 6 transcripts (splice variants), 397 orthologues and 22 paralogues. Biased expression in salivary gland (RPKM 748.1), liver (RPKM 688.6) and 5 other tissues.

功能概要

参与细胞粘附和检测参与苦味感官知觉的化学刺激。位于细胞外空间。 [由基因组资源联盟提供,2022 年 4 月]

Involved in cell adhesion and detection of chemical stimulus involved in sensory perception of bitter taste. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

AZGP1 基因产物(1)

mRNA Protein Name
NM_001185.4 NP_001176.1 zinc-alpha-2-glycoprotein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16237761 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IDA
IDA: 通过直接分析推断
9813179 GOA
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: 通过直接分析推断
24248522 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
24248522 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

AZGP1 蛋白结构

MHC_I

MHC_I: Class I Histocompatibility antigen, domains alpha 1 and 2 (26 - 201)

C1-set

C1-set: Immunoglobulin C1-set domain (215 - 291)

  • 0
  • 100
  • 200
  • 298 a.a.
蛋白主名 其他名称

zinc-alpha-2-glycoprotein

Alpha-2-glycoprotein, zinc

重组 AZGP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70016 AZGP1 Protein, Human (HEK293, His) P25311 (Q21-S298) ≥95%

关联疾病

疾病名称 别名
Breast Cyst

Cyst Of The Breast

Breast Cysts

Breast Disease

Breast Diseases

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus AZGP1 VGNC VGNC:26367
Canis familiaris AZGP1 VGNC VGNC:38327
Rattus norvegicus AZGP1 RGD RGD:2187
Felis catus AZGP1 VGNC VGNC:68915
Mus musculus AZGP1 MGD MGI:103163
Macaca mulatta AZGP1 VGNC VGNC:70201
Others AZGP1 NCBI