AZGP1 蛋白, Human (HEK293, His)

AZGP1 Proteinas, a key regulator, induces lipid degradation in adipocytes, contributing to fat loss in advanced cancer. Its potential binding to polyunsaturated fatty acids emphasizes its role in lipid metabolism. Interacting with PIP adds complexity to its functional role in cellular processes, highlighting the molecular interplay involved. AZGP1 Protein, Human (HEK293, His) is the recombinant human-derived AZGP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of AZGP1 Protein, Human (HEK293, His) is 278 a.a., with molecular weight of ~39-42 kDa.

Ca羧肽酶 B2 (CPB2) 在生理调节中发挥着关键作用，特别是在循环系统中。该酶在切割生物活性肽（包括激肽和过敏毒素）的 C 端精氨酸或赖氨酸残基方面表现出特异性，从而微调它们的活性和循环中的下游信号传导。此外，CPB2 通过选择性去除已被纤溶酶部分降解的纤维蛋白中的 C 末端赖氨酸残基，有助于下调纤维蛋白溶解。这种双重功能强调了 CPB2 在维持肽活性和凝血过程平衡中的关键作用，强调了其在生理背景下协调复杂调节机制的重要性。

Measured  by the ability of the immobilized protein to support the adhesion of MC3T3‑E1  mouse preosteoblast cells. The ED₅₀ for this effect is 0.0948 μg/mL ,  corresponding to a specific activity is 1.055×10⁴ U/mg.

Human

HEK293

C-6*His

P25311 (Q21-S298)

563  [NCBI]

QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS

Approximately 39-42 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.