2. Gene
  3. SLC39A10 - solute carrier family 39 member 10 Gene

SLC39A10 - solute carrier family 39 member 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 39 成员 10

种属: Homo sapiens

同用名: ZIP10; LZT-Hs2

基因 ID: 57181 | 基因类型: protein coding

关于 SLC39A10

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:195,613,029-195,737,700 (from NCBI)

This gene has 9 transcripts (splice variants), 185 orthologues and 6 paralogues. Broad expression in thyroid (RPKM 12.9), brain (RPKM 12.5) and 21 other tissues.

功能概要

锌是数百种酶的必需辅助因子。它参与蛋白质、核酸、碳水化合物和脂质代谢，以及基因转录、生长、发育和分化的控制。 SLC39A10 属于显示锌转运蛋白结构特征的蛋白质亚家族 (Taylor 和 Nicholson，2003 [PubMed 12659941]) 。[OMIM 提供，2008 年 3 月]

Zinc is an essential cofactor for hundreds of Enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

SLC39A10 基因产物(2)

mRNA Protein Name
NM_001127257.2 NP_001120729.1 zinc transporter ZIP10 precursor
NM_020342.3 NP_065075.1 zinc transporter ZIP10 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27274087 GOA
enables zinc ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
27274087 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
27274087 GOA
involved in zinc ion transmembrane transport IDA
IDA: 通过直接分析推断
27274087 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
30520657 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
27274087 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC39A10 蛋白结构

Zip

Zip: ZIP Zinc transporter (405 - 819)

  • 0
  • 200
  • 400
  • 600
  • 831 a.a.
蛋白主名 其他名称

zinc transporter ZIP10

ZIP-10

关联疾病

疾病名称 别名
Acrodermatitis Enteropathica, Zinc-Deficiency Type

Acrodermatitis Enteropathica

AEZ

Enteropathica

Brandt Syndrome

Ae

Acrodermatitis Enteropathica Zinc Deficiency Type

Danbolt-Cross Syndrome

Acrodermatitis Enteropathica, Zinc Deficiency Type

Inherited Zinc Deficiency

Acrodermatitis Enteropathica, Zinc Deficiency

Danbolt-Closs Syndrome

Primary Zinc Malabsorption Syndrome
Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3

Spondylocheirodysplasia, Ehlers-Danlos Syndrome-Like

Scd-Eds

EDSSPD3

Ehlers-Danlos Syndrome Spondylodysplastic Type 3

Ehlers-Danlos Syndrome, Spondylocheirodysplastic Type

Slc39a13-Related Spondylodysplastic Ehlers-Danlos Syndrome

Slc39a13-Related Speds

Slc39a13-Related Spondylodysplastic Eds

Spondylocheirodysplastic Ehlers-Danlos Syndrome

Speds-Slc39a13

Ehlers-Danlos Syndrome-Like Spondylocheirodysplasia

Ehlers-Danlos Syndrome, Spondylodysplastic, Type 3
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13229 SLC39A10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SLC39A10 VGNC VGNC:65354
Bos taurus SLC39A10 VGNC VGNC:34858
Macaca mulatta SLC39A10 VGNC VGNC:77540
Mus musculus SLC39A10 MGD MGI:1914515
Rattus norvegicus SLC39A10 RGD RGD:1307321
Canis familiaris SLC39A10 VGNC VGNC:57394
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