1. Gene
  2. CPLX3 - complexin 3 Gene

CPLX3 - complexin 3 Gene

中文名称:络合素 3

种属: Homo sapiens

同用名: CPXIII; CPX-III; Nbla11589

基因 ID: 594855 | 基因类型: protein coding

关于 CPLX3

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,826,627-74,831,802 (from NCBI)

This gene has 1 transcript (splice variant), 211 orthologues and 3 paralogues. Biased expression in prostate (RPKM 58.8), spleen (RPKM 33.7) and 3 other tissues.

功能概要

预测启用 SNARE 绑定活动。预计参与调节神经递质分泌和突触小泡胞吐。预测位于质膜和突触中。预计成为 SNARE 复合体的一部分。预计在光感受器带状突触和末端布顿中活跃。预测为突触前活动区膜的锚定成分和突触小泡膜的锚定成分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable SNARE binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to be located in plasma membrane and synapse. Predicted to be part of SNARE complex. Predicted to be active in photoreceptor ribbon synapse and terminal bouton. Predicted to be anchored component of presynaptic active zone membrane and anchored component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

CPLX3 基因产物(1)

mRNA Protein Name
NM_001030005.3 NP_001025176.1 complexin-3

CPLX3 蛋白结构

Synaphin

Synaphin: Synaphin protein (1 - 140)

  • 0
  • 100
  • 158 a.a.
蛋白主名 其他名称

complexin-3

CPX III

重组 CPLX3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76848 CPLX3 Protein, Human (HEK293, His) Q8WVH0 (M1-K154) ≥95%

关联疾病

疾病名称 别名
Chromosome 15q24 Deletion Syndrome

15q24 Microdeletion Syndrome

Del(15)(Q24)

Monosomy 15q24

15q24 Microdeletion

15q24 Deletion

Interstitial Deletion Of Chromosome 15q24

Noonan Syndrome 1

Noonan Syndrome

NS1

Male Turner Syndrome

Female Pseudo-Turner Syndrome

Turner Phenotype With Normal Karyotype

Noonan Syndrome With Pigmented Villonodular Synovitis

Turner'S Phenotype, Karyotype Normal

Familial Turner Syndrome

Noonan'S Syndrome

Noonan-Ehmke Syndrome

Ns

Pseudo-Ullrich-Turner Syndrome

Turner Syndrome In Female With X Chromosome

Turner-Like Syndrome

Ullrich-Noonan Syndrome

Noonan-Like/Multiple Giant Cell Lesion Syndrome

Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions

Pterygium Colli Syndrome

Noonan Syndrome, Type 1

Turner Syndrome, Male

Chromosome 22q11.2 Deletion Syndrome, Distal

22q11.2 Deletion Syndrome

Autosomal Dominant Opitz G/Bbb Syndrome

Catch22

Cayler Cardiofacial Syndrome

Conotruncal Anomaly Face Syndrome

Digeorge Syndrome

Sedlackova Syndrome

Shprintzen Syndrome

Velocardiofacial Syndrome

22q11.2 Distal Deletion Syndrome

Distal 22q11.2 Microdeletion Syndrome

22q11.2ds

Vcfs

Velo-Cardio-Facial Syndrome

Distal Chromosome 22q11.2 Deletion Syndrome

Chromosome 22q11.2 Deletion Syndrome Distal

Chromosome 22q11.2 Deletion Syndrome

Deletion 22q11.2 Syndrome

22q11ds

Catch 22

Digeorge Sequence

Microdeletion 22q11.2

Monosomy 22q11

Takao Syndrome

Distal Del(22)(Q11.2)

Distal Monosomy 22q11.2

Catch 22 Syndrome

Chromosome Deletion Syndrome 22q11.2, Distal

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus CPLX3 VGNC VGNC:27653
Macaca mulatta CPLX3 VGNC VGNC:84328
Mus musculus CPLX3 MGD MGI:2384571
Canis familiaris CPLX3 VGNC VGNC:39557
Felis catus CPLX3 VGNC VGNC:61124
Rattus norvegicus CPLX3 RGD RGD:1560104
Others CPLX3 NCBI