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  2. Ntsr2 - neurotensin receptor 2 Gene

Ntsr2 - neurotensin receptor 2 Gene

中文名称:神经降压素受体 2

种属: Rattus norvegicus

基因 ID: 64636 | 基因类型: protein coding

关于 Ntsr2

Primary_assembly 6: 39,424,324-39,431,014 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 79 orthologues, 14 paralogues and is associated with 1 phenotype. Restricted expression toward (RPKM 7.4).

功能概要

实现相同的蛋白质结合活性。参与 ERK1ERK2 级联的正向调节。位于多个细胞成分中,包括树突状轴;核周;和跨高尔基网络。与人类 NTSR2(神经降压素受体 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Involved in positive regulation of ERK1 and ERK2 cascade. Located in several cellular components, including dendritic shaft; perikaryon; and trans-Golgi network. Orthologous to human NTSR2 (Neurotensin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr2 基因产物(1)

mRNA Protein Name
NM_022695.2 NP_073186.1 neurotensin receptor type 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17188644 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17188644 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
16564027 RGD
involved in positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
12084713 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
16564027 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
16564027 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
16564027 RGD
located in trans-Golgi network IDA
IDA: 通过直接分析推断
16564027 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Ntsr2 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 368)

7tm_GPCRs

7tm_GPCRs: cd14964 (34 - 58)

7tm_GPCRs

7tm_GPCRs: cd14964 (68 - 90)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 130)

7tm_GPCRs

7tm_GPCRs: cd14964 (153 - 169)

7tm_GPCRs

7tm_GPCRs: cd14964 (203 - 226)

7tm_GPCRs

7tm_GPCRs: cd14964 (295 - 317)

7tm_GPCRs

7tm_GPCRs: cd14964 (336 - 361)

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  • 300
  • 416 a.a.
蛋白主名 其他名称

neurotensin receptor type 2

NT-R-2

NTR2 receptor

high-affinity levocabastine-sensitive neurotensin receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntsr2 NCBI NCBI:23620