1. Gene
  2. Rps6ka6 - ribosomal protein S6 kinase polypeptide 6 Gene

Rps6ka6 - ribosomal protein S6 kinase polypeptide 6 Gene

中文名称:核糖体蛋白 S6 激酶多肽 6

种属: Mus musculus

同用名: RSK4; S6K-alpha-6; 2610524K04Rik

基因 ID: 67071 | 基因类型: protein coding

关于 Rps6ka6

Chromosome X: 110,297,889-110,447,656 reverse strand.GRCm39:CM001013.3

This gene has 11 transcripts (splice variants), 207 orthologues, 7 paralogues and is associated with 9 phenotypes. Biased expression in placenta adult (RPKM 15.3), CNS E11.5 (RPKM 4.6) and 7 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动核糖体蛋白 S6 激酶活性。参与 ERK1ERK2 级联的负调控;胚胎发育的负调控;和中胚层发育的负调控。预测位于纤维中心和线粒体。预计在细胞质和核质中有活性。以多种结构表达,包括泌尿生殖系统;神经系统;鼻子;呼吸系统;和胸腺原基。与人 RPS6KA6(核糖体蛋白 S6 激酶 A6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ribosomal protein S6 kinase activity. Involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of embryonic development; and negative regulation of mesoderm development. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including genitourinary system; nervous system; nose; respiratory system; and thymus primordium. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka6 基因产物(3)

mRNA Protein Name
NM_001398774.1 NP_001385703.1 ribosomal protein S6 kinase alpha-6 isoform 2
NM_001374707.3 NP_001361636.2 ribosomal protein S6 kinase alpha-6 isoform 2
NM_025949.3 NP_080225.2 ribosomal protein S6 kinase alpha-6 isoform 1

Rps6ka6 蛋白结构

STKc_RSK_N

STKc_RSK_N: cd05582 (192 - 506)

STKc_RSK_C

STKc_RSK_C: cd14091 (541 - 827)

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  • 860 a.a.
蛋白主名 其他名称

ribosomal protein S6 kinase alpha-6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rps6ka6 NCBI NCBI:27330