2. Gene
  3. Slc39a8 - solute carrier family 39 (metal ion transporter), member 8 Gene

Slc39a8 - solute carrier family 39 (metal ion transporter), member 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Zip8; ZIP-8; BIGM103; 4933419D20Rik

基因 ID: 67547 | 基因类型: protein coding

关于 Slc39a8

功能概要

Enables anion:cation symporter activity and transition metal ion transmembrane transporter activity. Involved in bicarbonate transport; cellular transition metal ion homeostasis; and ion transmembrane transport. Acts upstream of or within cadmium ion transmembrane transport. Located in apical plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; metanephros; and reproductive system. Used to study left ventricular noncompaction. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc39a8 基因产物(3)

mRNA Protein Name
NM_001135149.1 NP_001128621.1 metal cation symporter ZIP8 precursor
NM_001135150.1 NP_001128622.1 metal cation symporter ZIP8 precursor
NM_026228.5 NP_080504.3 metal cation symporter ZIP8 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoatomic cation:bicarbonate symporter activity IDA
IDA: 通过直接分析推断
16638970 MGI
enables zinc:bicarbonate symporter activity IDA
IDA: 通过直接分析推断
18037372 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of DNA-templated transcription IMP
IMP: 通过突变表型推断
24529376 MGI
acts upstream of arginine metabolic process IMP
IMP: 通过突变表型推断
28481222 MGI
involved in bicarbonate transport IDA
IDA: 通过直接分析推断
16638970 MGI
acts upstream of or within cadmium ion transmembrane transport IDA
IDA: 通过直接分析推断
15722412 MGI
involved in cadmium ion transmembrane transport IDA
IDA: 通过直接分析推断
16638970 MGI
involved in cadmium ion transmembrane transport IMP
IMP: 通过突变表型推断
30015240 MGI
acts upstream of cartilage homeostasis IMP
IMP: 通过突变表型推断
24529376 MGI
acts upstream of extracellular matrix organization IMP
IMP: 通过突变表型推断
29337306 MGI
involved in intracellular manganese ion homeostasis IMP
IMP: 通过突变表型推断
28481222 MGI
involved in intracellular zinc ion homeostasis IDA
IDA: 通过直接分析推断
24529376 MGI
involved in iron ion import across plasma membrane IDA
IDA: 通过直接分析推断
22898811 MGI
involved in iron ion import across plasma membrane IMP
IMP: 通过突变表型推断
30015240 MGI
acts upstream of leukocyte adhesion to arterial endothelial cell IMP
IMP: 通过突变表型推断
30015240 MGI
involved in manganese ion transmembrane transport IDA
IDA: 通过直接分析推断
16638970 MGI
involved in manganese ion transmembrane transport IMP
IMP: 通过突变表型推断
28481222 MGI
involved in mercury ion transport IDA
IDA: 通过直接分析推断
16638970 MGI
involved in plasma membrane selenite transport IDA
IDA: 通过直接分析推断
27166256 MGI
acts upstream of protein N-linked glycosylation IMP
IMP: 通过突变表型推断
28481222 MGI
acts upstream of regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
29337306 MGI
involved in zinc ion import across plasma membrane IDA
IDA: 通过直接分析推断
18037372 MGI
involved in zinc ion import across plasma membrane IMP
IMP: 通过突变表型推断
29337306 MGI
involved in zinc ion transmembrane transport IMP
IMP: 通过突变表型推断
24529376 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16638970 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15722412 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metal cation symporter ZIP8

Zrt- and Irt-like protein 8

zinc transporter ZIP8

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16232 Slc39a8 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13239 SLC39A8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc39a8 NCBI NCBI:64116
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