1. Gene
  2. Gpr6 - G protein-coupled receptor 6 Gene

Gpr6 - G protein-coupled receptor 6 Gene

中文名称:G 蛋白偶联受体 6

种属: Rattus norvegicus

基因 ID: 83683 | 基因类型: protein coding

关于 Gpr6

Primary_assembly 20: 44,489,853-44,492,624 reverse strand.mRatBN7.2:CM026993.1

This gene has 1 transcript (splice variant), 186 orthologues and 18 paralogues. Restricted expression toward (RPKM 28.1).

功能概要

预计该基因编码的蛋白可启动鞘氨醇-1-磷酸受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和代谢过程的调控。预计在细胞溶质钙离子浓度的正调节上游或正调节内起作用。预计是膜的组成部分。预计在细胞质和质膜中有活性。与人类 GPR6(G 蛋白偶联受体 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR6 (G protein-coupled receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Gpr6 基因产物(1)

mRNA Protein Name
NM_031806.2 NP_113994.1 G-protein coupled receptor 6

Gpr6 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (73 - 340)

7tm_GPCRs

7tm_GPCRs: cd14964 (75 - 99)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 129)

7tm_GPCRs

7tm_GPCRs: cd14964 (142 - 164)

7tm_GPCRs

7tm_GPCRs: cd14964 (187 - 203)

7tm_GPCRs

7tm_GPCRs: cd14964 (223 - 246)

7tm_GPCRs

7tm_GPCRs: cd14964 (278 - 300)

7tm_GPCRs

7tm_GPCRs: cd14964 (308 - 333)

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  • 363 a.a.
蛋白主名 其他名称

G-protein coupled receptor 6

putative G protein-coupled receptor (CNL3)

sphingosine 1-phosphate receptor GPR6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr6 NCBI NCBI:2830