2. Gene
  3. Ackr3 - atypical chemokine receptor 3 Gene

Ackr3 - atypical chemokine receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：非典型趋化因子受体 3

种属: Rattus norvegicus

同用名: Rdc1; Cxcr7; Cmkor1

基因 ID: 84348 | 基因类型: protein coding

关于 Ackr3

Primary_assembly 9: 90,799,686-90,811,237 forward strand.mRatBN7.2:CM026982.1

This gene has 6 transcripts (splice variants), 252 orthologues, 24 paralogues and is associated with 12 phenotypes. Biased expression in Heart (RPKM 129.4), Lung (RPKM 118.2) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动趋化因子结合活性；趋化因子受体活性；和清道夫受体活性。参与间充质干细胞迁移的正调控。位于细胞质中；核;和质膜。与人类 ACKR3（非典型趋化因子受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chemokine binding activity; Chemokine Receptor activity; and scavenger receptor activity. Involved in positive regulation of mesenchymal stem cell migration. Located in cytoplasm; nucleus; and plasma membrane. Orthologous to human ACKR3 (atypical Chemokine Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ackr3 基因产物(1)

mRNA Protein Name
NM_053352.2 NP_445804.1 atypical chemokine receptor 3
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of mesenchymal stem cell migration IMP
IMP: 通过突变表型推断
24924806 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Ackr3 蛋白结构

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (44 - 325)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (45 - 71)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (78 - 102)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (116 - 146)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (159 - 180)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (208 - 235)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (244 - 274)

7tmA_ACKR3_CXCR7

7tmA_ACKR3_CXCR7: cd14987 (293 - 318)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
蛋白主名 其他名称

atypical chemokine receptor 3

C-X-C chemokine receptor type 7

CXC-R7

CXCR-7

G-protein coupled receptor RDC1 homolog

RDC-1

chemokine (C-X-C motif) receptor 7

chemokine orphan receptor 1

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123813 CCX-777 Agonist 98.73% 否
HY-159582 ACKR3 agonist 1 Agonist / 否
HY-161414 trans-VUF25471 / 否
HY-D2201 Fluorescent ACKR3 antagonist 1 / 否
HY-RS00162 ACKR3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00163 Ackr3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00164 Ackr3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ackr3 NCBI NCBI:57007
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