2. Gene
  3. CREG1 - cellular repressor of E1A stimulated genes 1 Gene

CREG1 - cellular repressor of E1A stimulated genes 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：E1A 刺激基因 1 的细胞阻遏物

种属: Homo sapiens

同用名: CREG

基因 ID: 8804 | 基因类型: protein coding

关于 CREG1

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:167,541,013-167,553,762 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in gall bladder (RPKM 83.3), thyroid (RPKM 78.7) and 25 other tissues.

功能概要

腺病毒 E1A 蛋白既可以激活也可以抑制基因表达，从而促进细胞增殖并抑制分化。由该基因编码的蛋白质拮抗 E1A 的转录激活和细胞转化。该蛋白与 E1A 具有有限的序列相似性，并在体外结合一般转录因子 TBP 和肿瘤抑制因子 pRb。该基因可能有助于细胞生长和分化的转录控制。[RefSeq 提供，2008 年 7 月]

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]

CREG1 基因产物(1)

mRNA Protein Name
NM_003851.3 NP_003842.1 protein CREG1 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
25645918 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CREG1 蛋白结构

Pyrid_oxidase_2

Pyrid_oxidase_2: Pyridoxamine 5'-phosphate oxidase (50 - 216)

  • 0
  • 100
  • 200
  • 220 a.a.
蛋白主名 其他名称

protein CREG1

重组 CREG1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7849 CREG1/CREG Protein, Human (HEK293, His) O75629 (R32-Q220) ≥95%

关联疾病

疾病名称 别名
Embryonal Carcinoma

Embryonal Neoplasm

Embryonal Cancer

Primary Extragonadal Embryonal Carcinoma

Embryo Neoplasm

Carcinoma Embryonal

Cancer Embryonal

Carcinoma, Embryonal

Extragonadal Embryonal Carcinoma

Cancer, Embryonal
Ornithosis

Psittacosis

Chlamydial Pneumonia

Chlamydia Psittaci Infection

Chlamydia Psittaci
Spondyloarthropathy

Spondylarthropathies

Spondarthropathy

Spondylarthrosis

Spondyloarthropathy, Susceptibility To

Spondylarthritis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03161 CREG1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CREG1 VGNC VGNC:61174
Canis familiaris CREG1 VGNC VGNC:39605
Bos taurus CREG1 VGNC VGNC:27702
Macaca mulatta CREG1 VGNC VGNC:106346
Rattus norvegicus CREG1 RGD RGD:1306804
Mus musculus CREG1 MGD MGI:1344382
Others CREG1 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z