Age-related decline in hippocampal tyrosine phosphatase PTPRO is a mechanistic factor in chemotherapy-related cognitive impairment

Affiliations

• 1 Department of Urology Surgery, and.
• 2 Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, China.
• 3 Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou, Guangdong, China.
• 4 Department of Pathology, The First People's Hospital of Foshan, Foshan, Guangdong, China.
• 5 Department of Thoracic Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, China.
• 6 Graduate School, Shantou University Medical College, Shantou, Guangdong, China.
• 7 Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
• 8 Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People's Republic of China, School of Medicine, Jinan University, Guangzhou, Guangdong, China.
• 9 Shantou University Mental Health Center.
• 10 National Key Disciplines, Department of Forensic and Pathology, and.
• 11 Center for Neuroscience, Shantou University Medical College, Shantou, Guangdong, China.
• 12 Cell Biology Department, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
• 13 The Affiliated Kangning Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
• 14 Department of Urology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
• 15 Minister of Education Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, Guangdong, China.
• 16 Gene Editing Center, School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China.
• 17 Department of Emergency Medicine and Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• 18 Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA.
• 19 Institute of Precision Cancer Medicine and Pathology, School of Medicine, and Minister of Education Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, Guangdong, China.