2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. O-Demethyl Lenvatinib

O-Demethyl Lenvatinib 是 Lenvatinib (HY-10981) 的代谢物。Lenvatinib (E7080) 一种具有口服活性的，多靶点酪氨酸激酶抑制剂，VEGFR1-3、FGFR1-4、PDGFR、KIT 和 RET，显示有效抗癌的活性。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 O-Demethyl Lenvatinib hydrochloride 通常具有更好的水溶性和稳定性。

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O-Demethyl Lenvatinib Chemical Structure

O-Demethyl Lenvatinib Chemical Structure

CAS No. : 417717-04-5

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O-Demethyl Lenvatinib 的其他形式现货产品:

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O-Demethyl Lenvatinib 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

O-Demethyl Lenvatinib is a metabolite of Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2].

分子量

412.83

Formula

C20H17ClN4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

O-Demethyl Lenvatinib 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Demethyl Lenvatinib417717-04-5Drug MetaboliteInhibitorinhibitorinhibit

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