1. 重组蛋白
  2. CD Antigens Fc Receptors Biotinylated Proteins
  3. Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins Fc-gamma Receptor
  4. Fc gamma RII/CD32
  5. FcγRIIB/CD32b
  6. Fc gamma RIIB/CD32b 蛋白, Mouse (Biotinylated, HEK293, His-Avi)

Fc gamma RIIB/CD32b 蛋白, Mouse (Biotinylated, HEK293, His-Avi)

目录号: HY-P75649
产品使用指南

Fc gamma RIIB/CD32b 蛋白对于 IgG 结合活性至关重要,并参与免疫反应和各种过程。它在抗原加工和呈递、免疫过程的负调节和吞噬作用中发挥作用。Fc gamma RIIB/CD32b 蛋白, Mouse (Biotinylated, HEK293, His-Avi) 是重组的 Fc gamma RIIB/CD32b 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。

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100 μg   询价  

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描述

Fc gamma RIIB/CD32b protein is essential for IgG binding activity and participates in immune responses and various processes. It plays a role in antigen processing and presentation, negative regulation of immune processes, and phagocytosis. Fc gamma RIIB/CD32b Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

研究背景

Fc gamma RIIB/CD32b 蛋白通过启用 IgG 结合活性发挥着至关重要的作用,表明其参与免疫反应。该蛋白参与多种过程,例如细胞对淀粉样蛋白的反应、神经系统发育和细胞对应激反应的调节,在包括抗原加工和通过 MHC II 类呈递外源肽抗原、负调节免疫效应过程和吞噬作用的调节。它战略性地位于细胞体、树突棘和质膜的外侧,作为膜的一个组成部分发挥作用。Fc gamma RIIB/CD32b 在肾脏 (RPKM 19.1)、脾脏 (RPKM 16.7) 和 21 个其他组织等组织中广泛表达,证明了其在各种生理环境中的免疫调节中的重要性。该基因的人类直系同源物与多种疾病有关,包括自身免疫性疾病、登革热病、血液癌症、白细胞减少症和疟疾,强调了其在健康和疾病中的关键作用。

种属

Mouse

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

A0A0B4J1E6/NP_001070657 (M1-R217)

基因 ID
蛋白结构
N-term
CD32b (M1-R217)
Accession # A0A0B4J1E6/NP_001070657
Avi-His
C-term
同用名
Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; FcRII-b; CD32; FCGR2B; FCG2; IGFR2
分子量

38-43 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Fc gamma RIIB/CD32b Protein, Mouse (Biotinylated, HEK293, His-Avi)
目录号:
HY-P75649
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