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2'-Deoxyuridine (Standard)

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Cat. No. Product Name Target Research Area Chemical Structure
  • HY-D0186R

    Endogenous Metabolite Thymidylate Synthase Infection
    2'-脱氧尿苷 (Standard) 2'-Deoxyuridine (Standard) 是 2'-Deoxyuridine 的分析标准品。本产品用于研究及分析应用。2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD).
    2'-Deoxyuridine (Standard)
  • HY-W424779R

    Drug Metabolite Infection
    5-羧基-2'-脱氧尿苷 (Standard) 5-Carboxy-2′-deoxyuridine (Standard)是 5-Carboxy-2′-deoxyuridine 的分析标准品。本产品用于研究及分析应用。5-Carboxy-2'-deoxyuridine 是 Trifluridine 的代谢物。5-Carboxy-2'-deoxyuridine 是胸苷的甲基氧化产物,可通过甲萘醌介导的胸苷光敏作用形成。
    5-Carboxy-2′-deoxyuridine (Standard)
  • HY-B0307R

    Phosphatase Orthopoxvirus Infection Cancer
    碘苷 (Standard) Idoxuridine (Standard) 是 Idoxuridine 的分析标准品。本产品用于研究及分析应用。Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) 是一种碘化的胸苷类似物,可竞争性抑制磷酸化酶 (phosphorylases)。 Idoxuridine 可以通过抑制 DNA 聚合酶 (DNA polymerase),影响病毒的复制,从而抑制病毒活性,特别是眼部病毒性感染,包括单纯疱疹性角膜炎。Idoxuridine 作用于猫疱疹病毒的 IC50 值为 4.3 μM。Idoxuridine 具有抗正痘病毒活性。
    Idoxuridine (Standard)
  • HY-B0021R

    Ro 21-9738 (Standard); 5-Fluoro-5'-Deoxyuridine (Standard); 5'-DFUR (Standard)

    Thymidylate Synthase Cancer
    去氧氟尿苷 (标准品); Doxifluridine (Standard) 是 Doxifluridine 的分析标准品。本产品用于研究及分析应用。Doxifluridine 具有抗癌活性。Doxifluidine 是一种 5-FU 前药。Doxifluridine 是胸腺嘧啶酸合酶抑制剂。 Doxifluridine 能通过协同多种药物增强对肿瘤的抑制。
    Doxifluridine (Standard)

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