2. 天然产物
  3. 植物 黄酮类 酚类
  4. 龙胆科 黄酮 氧杂蒽酮
  5. 獐牙菜
  6. Swertianine

Swertianine  (Synonyms: 当药宁)

目录号: HY-N1994
产品使用指南

摩尔计算器

Swertianine 是一种羟基氧杂蒽酮，能从全株獐牙菜中分离得到。Swertianine 抑制脂质过氧化，清除 DPPH 和超氧自由基，具有抗氧化活性。Swertianine 还抑制 γ 射线诱导的 pBR322 DNA 损伤，具有保护作用。

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Swertianine Chemical Structure

Swertianine Chemical Structure

CAS No. : 20882-75-1

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Swertianine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
C6 IC50
31.4 μM
Compound: 1
Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay
Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay
[PMID: 18406151]
U-251 IC50
27.3 μM
Compound: 1
Antiproliferative activity against human U251 cells assessed as cell number after 48 hrs by crystal violet assay
Antiproliferative activity against human U251 cells assessed as cell number after 48 hrs by crystal violet assay
[PMID: 18406151]
分子量

274.23

Formula

C14H10O6
CAS 号
中文名称

当药宁
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Swertianine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Swertianine20882-75-1当药宁Inhibitorinhibitorinhibit

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