2. Metabolic Enzyme/Protease
  3. PCSK9
  4. Tafolecimab

Tafolecimab  (Synonyms: 托莱西单抗; IBI-306)

目录号: HY-P99552 纯度: 95.04%
COA

摩尔计算器

Tafolecimab (IBI-306) 是一种人源 lgG2 单克隆抗体，可特异性结合 PCSK-9 并通过抑制 PCSK-9 介导的低密度脂蛋白受体的内吞作用降低 LDL-C 水平，进而增强对 LDL-C 的清除，导致 LDL-C 水平降低。Tafolecimab 可用于高胆固醇血症的研究。

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CAS No. : 2225109-03-3

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9500
In-stock
10 mg   询价  
50 mg   询价  

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Tafolecimab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia[1].

同型

Human IgG2 kappa
推荐同型对照抗体
种属

Human
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

托莱西单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG2 kappa
纯度 & 产品资料
参考文献

Tafolecimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tafolecimab2225109-03-3IBI-306托莱西单抗IBI306IBI 306PCSK9Proprotein convertase subtilisin/kexin type 9lgG2PCSK-9LDL-ChypercholesterolaemiaInhibitorinhibitorinhibit

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