1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Cathepsin HSP
  3. Tasiamide B

Tasiamide B 是一种 Cathepsin D 抑制剂,是一种发现于海洋蓝藻 Symploca sp. 中的线性肽。Tasiamide B 被证明是开发天冬氨酸蛋白酶抑制剂的良好模板。Tasiamide B 通过与靶蛋白 HSP90 强烈相互作用而对皮肤癌有效。

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Tasiamide B Chemical Structure

Tasiamide B Chemical Structure

CAS No. : 587014-85-5

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  • 生物活性

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生物活性

Tasiamide B is a Cathepsin D inhibitor, which is a linear peptide found in the marine cyanobacteria Symploca sp.. Tasiamide B is proved as a good template for the development of aspartic proteases inhibitors. Tasiamide B is effective against skin cancer by strongly interacting with the target protein HSP90[1][2].

IC50 & Target

HSP90

 

Cathepsin D

 

分子量

979.17

Formula

C50H74N8O12

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tasiamide B
目录号:
HY-N15154
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