1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Cathepsin Inhibitors

Cathepsin Inhibitors

Cathepsin B

Cathepsin C

Cathepsin D

Cathepsin E

Cathepsin K

Cathepsin L

Cathepsin S

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Cathepsin Inducers, Inhibitors, Antagonists & Activators
Product Name Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S Purity
E-64        
cathepsin K
cathepsin L
  99.96%
CA-074 methyl ester
Cathepsin B
            99.62%
Calpeptin        
cathepsin K
    ≥98.0%
CA-074
Cathepsin B
            99.88%
L-Homocysteine          
cathepsin L
  ≥98.0%
LY 3000328            
cathepsin S
98.00%
Z-FY-CHO          
cathepsin L
 
Odanacatib        
cathepsin K
    99.82%
SID 26681509          
cathepsin L
  98.70%
Z-FA-FMK
Cathepsin B
       
cathepsin L
  99.14%
Balicatib
Cathepsin B, IC50: 61 nM
     
cathepsin K, IC50: 22 nM
cathepsin L, IC50: 48 nM
cathepsin S, IC50: 2900 nM
98.00%
Cathepsin L-IN-2
Cathepsin B
       
cathepsin L
  98.27%
Hepcidin-1 (mouse) (TFA)        
cathepsin K
    98.94%
Z-WEHD-FMK
Cathepsin B
            ≥98.0%
LHVS
Cathepsin B
     
cathepsin K
cathepsin L
cathepsin S
98.03%
Cathepsin C-IN-5  
Cathepsin C
         
Petesicatib            
cathepsin S
99.66%
GSK-2793660  
Cathepsin C
          99.91%
Relacatib        
cathepsin K
cathepsin L
  99.99%
L-006235
Cathepsin B
     
cathepsin K
    99.96%
RO5461111            
human Cathepsin S, IC50: 0.4 nM
murine Cathepsin S, IC50: 0.5 nM
98.17%
VBY-825        
cathepsin K
 
cathepsin S
99.81%
ONO-5334        
cathepsin K
    99.83%
Aurantiamide acetate          
cathepsin L
  99.60%
3-Epiursolic Acid          
cathepsin L, IC50: 6.5 μM
  99.77%
Gü2602        
cathepsin K
    98.13%
Z-Phe-Tyr(tBu)-diazomethylketone          
cathepsin L
  ≥99.0%
Cathepsin K inhibitor 6
Cathepsin B, IC50: 0.3 μM
     
cathepsin K, IC50: 17 nM
cathepsin L, IC50: 0.05 μM
  98.18%
Hepcidin-1 (mouse)        
cathepsin K
   
MIV-247            
cathepsin S
Cathepsin D and E FRET Substrate    
Cathepsin D
Cathepsin E
     
TS-24            
cathepsin S, IC50: 4.3 μM
98.96%
Cathepsin K inhibitor 3        
cathepsin K, IC50: 0.5 nM
   
FGA146          
cathepsin L, Ki: 0.87 μM
 
Cathepsin L-IN-4          
cathepsin L
 
Cathepsin Inhibitor 4            
cathepsin S, Ki: 0.04 nM
CAA-0225          
cathepsin L
 
Cathepsin L/S-IN-1          
cathepsin L, IC50: 4.10 μM
cathepsin S, IC50: 1.79 μM
JNJ 10329670            
cathepsin S, Ki: 34 nM
ASPER-29          
cathepsin L, IC50: 6.03 μM
cathepsin S, IC50: 5.02 μM
SPR38
Cathepsin B, IC50: 11.1 ± 1.2 μM
       
cathepsin L, IC50: 1.92 ± 0.1 μM
 
ABP 25        
cathepsin K
   
SmCB1-IN-1
S. mansoni cathepsin B1, IC50: 0.05 μM
           
Cathepsin C-IN-3  
Cathepsin C
         
Cathepsin C-IN-4  
Cathepsin C
         
Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2    
Cathepsin D
       
Z-Arg-Arg-4MβNA triacetate
Cathepsin B
           
Ac-Leu-Val-Lys-Aldehyde
Cathepsin B, IC50: 4 nM
           
Mpro/Cathepsin L-IN-1          
cathepsin L
 
AM4299B
Cathepsin B, IC50: 0.7 μM
       
cathepsin L, IC50: 0.5 μM
 
Z-Phe-Phe-Diazomethylketone          
cathepsin L
 
Ac-VLPE-FMK
Cathepsin B
       
cathepsin L
  ≥99.0%
FGA145
Cathepsin B, Ki: 206 nM
       
cathepsin L, Ki: 53 nM
 
Cathepsin L-IN-5          
cathepsin L, IC50: 0.27 nM
 
SARS-CoV-2-IN-77          
cathepsin L, Ki: 111 nM
cathepsin S, Ki: 103 nM
SQ 32602      
Cathepsin E, IC50: 88 nM
     
S2160
Cathepsin B