2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Ac-Leu-Val-Lys-Aldehyde

Ac-Leu-Val-Lys-Aldehyde 是一种有效的组织蛋白酶 B (cathepsin B) 抑制剂，IC50 为 4 nM。Ac-Leu-Val-Lys-Aldehyde 显着减少喹啉酸 (HY-100807) 诱导的纹状体细胞死亡并导致 LC3-II 的积累。

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Custom Peptide Synthesis

Ac-Leu-Val-Lys-Aldehyde Chemical Structure

Ac-Leu-Val-Lys-Aldehyde Chemical Structure

CAS No. : 147600-40-6

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Ac-Leu-Val-Lys-Aldehyde 相关抗体

Top Publications Citing Use of Products

查看 Cathepsin 亚型特异性产品:

查看所有亚型
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC50s of 4 nM. Ac-Leu-Val-Lys-Aldehyde significantly reduces quinolinic acid (HY-100807)-induced striatal cell death and causes accumulation of LC3-II[1].

IC50 & Target[1]

Cathepsin B

4 nM (IC50)

分子量

384.51

Formula

C19H36N4O4
CAS 号
Sequence

Ac-Leu-Val-{Lys-Aldehyde}
Sequence Shortening

Ac-LV-{Lys-Aldehyde}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ac-Leu-Val-Lys-Aldehyde 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-Leu-Val-Lys-Aldehyde147600-40-6Cathepsinquinolinic acidstriatal cellLC3-IIP62Inhibitorinhibitorinhibit

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