1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. Cathepsin L-IN-5

Cathepsin L-IN-5 (D6-3) 是一种有效的 Cathepsin L (CatL) 抑制剂,IC50 值为 0.27 nM。Cathepsin L-IN-5 能够有效阻断 CatL 的功能,并通过抑制刺突蛋白的切割显著阻碍 SARS-CoV-2 假病毒进入细胞。Cathepsin L-IN-5 可用于 SARS-CoV-2 研究。

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Cathepsin L-IN-5 Chemical Structure

Cathepsin L-IN-5 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cathepsin L-IN-5 (D6-3) is a potent Cathepsin L (CatL) inhibitor with an IC50 of 0.27 nM. Cathepsin L-IN-5 effectively blocks the CatL function and substantially hinders the entry of the SARS-CoV-2 pseudovirus to cells by inhibiting the cleavage of the spike protein. Cathepsin L-IN-5 can be utilized in SARS-CoV-2 research[1].

IC50 & Target

cathepsin L

0.27 nM (IC50)

分子量

516.99

Formula

C30H26ClFN2O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Cathepsin L-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Cathepsin L-IN-5
目录号:
HY-169171
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