2. Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein
  3. Potassium Channel mAChR Calcium Channel
  4. Terodiline

Terodiline  (Synonyms: 特罗地林)

目录号: HY-16489
产品使用指南

摩尔计算器

Terodiline 是一种解痉剂，可阻断 hERG 电流，IC50 为 375 nM。Terodiline 具有抗胆碱能 (anticholinergic) 和钙拮抗剂 (calcium) 特性，可有效减少逼尿肌不稳定引起的异常膀胱收缩，可用于尿失禁的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Terodiline Chemical Structure

Terodiline Chemical Structure

CAS No. : 15793-40-5

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥4550
1 - 2 周
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Terodiline:

Terodiline 相关抗体

Top Publications Citing Use of Products

查看 mAChR 亚型特异性产品:

查看所有亚型
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

查看 Calcium Channel 亚型特异性产品:

查看所有亚型
N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Terodiline, an antispasmodic agent, blocks hERG current with the IC50 of 375 nM. Terodiline has both anticholinergic and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence[1][2].

IC50 & Target

mAChR[1]
Ca2+ channel[1]
体内研究
(In Vivo)

Terodiline (80 mg/kg; S.C.) is equipotent in inhibiting intravesical bladder pressure and carbachol-induced salivary secretion (ID50= 24 and 35 mg/kg, respectively), and in increasing pupil diameter (ED50=59 mg/kg)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Fmale or male Hartley guinea pigs (200-600 g)[1]
Dosage: 80 mg/kg
Administration: Administered S.C.
Result: Yielded an ID50 of 24±6 mg/kg. Higher doses were Iethal.
分子量

281.44

Formula

C20H27N
CAS 号
中文名称

特罗地林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Terodiline 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terodiline15793-40-5特罗地林Potassium ChannelmAChRCalcium ChannelKcsAMuscarinic acetylcholine receptorCa2+ channelsCa channelshERG currentanticholinergiccalcium antagonisturinary incontinenceInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Terodiline
目录号：
HY-16489
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z