2. Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel Immunology/Inflammation GPCR/G Protein
  3. Endogenous Metabolite iGluR Histamine Receptor
  4. Toladryl

Toladryl  (Synonyms: 4-Methyldiphenhydramine)

目录号: HY-138110
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摩尔计算器

Toladryl 是一种 Diphenhydramine (HY-B0303) 的衍生物，能透过血脑屏障并具有口服活性，抗组胺和抗乙酰胆碱活性。Toladryl 抗乙酰胆碱活性大约是 Diphenhydramine (HY-B0303) 的十分之一，对抗组织胺引起的豚鼠致命剂量的保护作用是 Diphenhydramine (HY-B0303) 的 2-4 倍。Toladryl 的副作用比 Diphenhydramine (HY-B0303) 少且轻微，但在较高剂量下，可能会引起失眠、激动、定向障碍等中枢神经系统症状。Toladryl 可用于过敏性疾病的研究。

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Toladryl Chemical Structure

Toladryl Chemical Structure

CAS No. : 19804-27-4

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Toladryl 相关抗体

Top Publications Citing Use of Products

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AMPA Receptor NMDA Receptor Kainate Receptor

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Toladryl is a derivative of Diphenhydramine (HY-B0303), capable of penetrating the blood-brain barrier and possessing oral activity, as well as antihistamine and anticholinergic activities. The anticholinergic activity of Toladryl is approximately one-tenth that of Diphenhydramine (HY-B0303), and its protective effect against lethal doses of histamine in guinea pigs is 2 to 4 times that of Diphenhydramine (HY-B0303). The side effects of Toladryl are fewer and milder than those of Diphenhydramine (HY-B0303), but at higher doses, it may cause central nervous system symptoms such as insomnia, agitation, and disorientation. Toladryl can be used for research in allergic diseases[1].

分子量

269.38

Formula

C18H23NO
CAS 号
中文名称

苯海拉明EP杂质F (Orphenadrine USP Related Compound F) (Toladryl)；奥芬那君相关化合物F(USP)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Toladryl 相关分类

  • 摩尔计算器

  • 稀释计算器

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Toladryl19804-27-44-Methyldiphenhydramine苯海拉明EP杂质F (Orphenadrine USP Related Compound F) (Toladryl)奥芬那君相关化合物F(USP)Endogenous MetaboliteiGluRHistamine ReceptorIonotropic glutamate receptorsHistamineAcetylcholineAllergic diseasesDerivativesSide effectsInhibitorinhibitorinhibit

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