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  3. Toladryl

Toladryl  (Synonyms: 4-Methyldiphenhydramine)

目录号: HY-138110
产品使用指南

Toladryl 是一种 Diphenhydramine (HY-B0303) 的衍生物,能透过血脑屏障并具有口服活性,抗组胺和抗乙酰胆碱活性。Toladryl 抗乙酰胆碱活性大约是 Diphenhydramine (HY-B0303) 的十分之一,对抗组织胺引起的豚鼠致命剂量的保护作用是 Diphenhydramine (HY-B0303) 的 2-4 倍。Toladryl 的副作用比 Diphenhydramine (HY-B0303) 少且轻微,但在较高剂量下,可能会引起失眠、激动、定向障碍等中枢神经系统症状。Toladryl 可用于过敏性疾病的研究。

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Toladryl Chemical Structure

Toladryl Chemical Structure

CAS No. : 19804-27-4

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Other Forms of Toladryl:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Toladryl is a derivative of Diphenhydramine (HY-B0303), capable of penetrating the blood-brain barrier and possessing oral activity, as well as antihistamine and anticholinergic activities. The anticholinergic activity of Toladryl is approximately one-tenth that of Diphenhydramine (HY-B0303), and its protective effect against lethal doses of histamine in guinea pigs is 2 to 4 times that of Diphenhydramine (HY-B0303). The side effects of Toladryl are fewer and milder than those of Diphenhydramine (HY-B0303), but at higher doses, it may cause central nervous system symptoms such as insomnia, agitation, and disorientation. Toladryl can be used for research in allergic diseases[1].

分子量

269.38

Formula

C18H23NO

CAS 号
中文名称

苯海拉明EP杂质F (Orphenadrine USP Related Compound F) (Toladryl);奥芬那君相关化合物F(USP)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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