1. Anti-infection
  2. Antibiotic
  3. Tosatoxumab

Tosatoxumab  (Synonyms: 托萨托舒单抗; KBSA301; AR-301)

目录号: HY-P99551 纯度: 95.00%
COA

Tosatoxumab (AR-301; KBSA301) 是一种人免疫球蛋白 G1 单克隆抗体,可特异性中和金黄色葡萄球菌的 α 毒素 (α-溶血素; Hla)。Tosatoxumab 与 α 毒素的 N 末端表位结合,从而防止功能性毒素孔寡聚化。Tosatoxumab 有潜力作为标准抗生素辅助疗法用于金黄色葡萄球菌肺炎的被动免疫疗法。

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CAS No. : 1374419-41-6

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规格 价格 是否有货 数量
1 mg ¥3000
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5 mg ¥7800
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent[1][2].

同型

Human IgG1 lambda1

推荐同型对照抗体
种属

Human

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

托萨托舒单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 lambda
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tosatoxumab
目录号:
HY-P99551
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