2. Protein Tyrosine Kinase/RTK
  3. PDGFR
  4. Tyrphostin AG1433 hydrochloride

Tyrphostin AG1433 hydrochloride  (Synonyms: SU1433 hydrochloride; AG1433 hydrochloride)

目录号: HY-119757A
产品使用指南

摩尔计算器

Tyrphostin AG 1433 是 PDGFR-β 和KDR/Flk-1 的特异性有效抑制剂。Tyrphostin AG 1433 作为血管生成抑制剂。

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Tyrphostin AG1433 hydrochloride Chemical Structure

Tyrphostin AG1433 hydrochloride Chemical Structure

CAS No. : 168836-03-1

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Tyrphostin AG1433 hydrochloride 的其他形式现货产品:

Other Forms of Tyrphostin AG1433 hydrochloride:

Tyrphostin AG1433 hydrochloride 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Tyrphostin AG 1433 is a specific and potent inhibitor of PDGFR-β and of KDR/Flk-1. Tyrphostin AG 1433 acts as an angiogenesis inhibitor[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BE IC50
> 50 μM
Compound: 15; SU1433
Antiangiogenic activity in human BE cells after 24 hrs by MTT assay
Antiangiogenic activity in human BE cells after 24 hrs by MTT assay
[PMID: 30502116]
HUVEC IC50
24.65 μM
Compound: 15; SU1433
Antiangiogenic activity in HUVEC after 24 hrs by MTT assay
Antiangiogenic activity in HUVEC after 24 hrs by MTT assay
[PMID: 30502116]
U-87MG ATCC IC50
> 50 μM
Compound: 15; SU1433
Antiangiogenic activity in human U87cells after 24 hrs by MTT assay
Antiangiogenic activity in human U87cells after 24 hrs by MTT assay
[PMID: 30502116]
分子量

302.76

Formula

C16H15ClN2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tyrphostin AG1433 hydrochloride 相关分类

  • 摩尔计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tyrphostin AG1433168836-03-1SU1433AG1433Tyrphostin AG 1433Tyrphostin AG-1433SU 1433SU-1433AG 1433AG-1433PDGFRPlatelet-derived growth factor receptorInhibitorinhibitorinhibit

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