1. Epigenetics Protein Tyrosine Kinase/RTK JAK/STAT Signaling Stem Cell/Wnt
  2. JAK
  3. YLIU-4-105-1

YLIU-4-105-1 是一种 II 型 JAK2 抑制剂。YLIU-4-105-1 具有体内药效活性,通过抑制 pSTAT5、减轻脾脏重量以及以剂量依赖性方式降低血液网织红细胞计数来证明。

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YLIU-4-105-1 Chemical Structure

YLIU-4-105-1 Chemical Structure

CAS No. : 2417685-83-5

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生物活性

YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner[1].

分子量

605.65

Formula

C32H34F3N7O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
YLIU-4-105-1
目录号:
HY-167846
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