2. Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein
  3. Calcium Channel Adrenergic Receptor
  4. YM-430

YM-430 是一种具有口服活性的钙进入阻断剂和 β -肾上腺素受体阻断剂。YM-430 抑制 Amifampridine (HY-14946) 诱导的节律性收缩，其 IC50 值为 59.2 nM；抑制精氨酸加压素诱导的 ST 段抑制，其 IC50 值为 36.6 mg/kg。YM-430 可用于心绞痛的研究。

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YM-430 Chemical Structure

YM-430 Chemical Structure

CAS No. : 153192-22-4

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YM-430 相关抗体

Top Publications Citing Use of Products

查看 Calcium Channel 亚型特异性产品:

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris[1].

分子量

553.60

Formula

C29H35N3O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

YM-430 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YM-430153192-22-4YM430YM 430Calcium ChannelAdrenergic ReceptorCa2+ channelsCa channelsBeta ReceptorAntianginal effectsangina modelsInhibitorinhibitorinhibit

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