2. Apoptosis
  3. Apoptosis
  4. 3-Hydroxyterphenyllin

3-Hydroxyterphenyllin  (Synonyms: NSC 299113)

目录号: HY-N10268
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摩尔计算器

3-Hydroxyterphenyllin 是 Aspergillus candidus 的代谢物。3-Hydroxyterphenyllin 抑制增殖并对 A2780/CP70 和 OVCAR-3 细胞产生细胞毒性。3-Hydroxyterphenyllin 诱导 S 期阻滞和细胞凋亡 (apoptosis)。3-Hydroxyterphenyllin 具有研究卵巢癌的潜力。

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3-Hydroxyterphenyllin Chemical Structure

3-Hydroxyterphenyllin Chemical Structure

CAS No. : 66163-76-6

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规格 是否有货
5 mg 询价

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3-Hydroxyterphenyllin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
34.68 μM
Compound: 11
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
[PMID: 21486068]
HL-60 IC50
9.86 μM
Compound: 11
Cytotoxicity against human HL60 cells by MTT assay
Cytotoxicity against human HL60 cells by MTT assay
[PMID: 21486068]
P388 IC50
28.06 μM
Compound: 11
Cytotoxicity against mouse P388 cells by MTT assay
Cytotoxicity against mouse P388 cells by MTT assay
[PMID: 21486068]
分子量

354.35

Formula

C20H18O6
CAS 号
结构分类
初始来源

Aspergillus candidus LINK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Hydroxyterphenyllin 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

3-Hydroxyterphenyllin66163-76-6NSC 299113NSC299113NSC-299113ApoptosisAspergillus candidusproliferationcytotoxicityS phase arrestapoptosisovarian cancerInhibitorinhibitorinhibit

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