2. Neuronal Signaling
  3. Amyloid-β Cholinesterase (ChE)
  4. AChE/Aβ-IN-5

AChE/Aβ-IN-5 (compound AV-2) 是一种双功能抑制剂，可靶向 AChE 和自身诱导的 Aβ (Amyloid-β) 聚集。AChE/Aβ-IN-5 能够显著改善小鼠受东莨菪碱和 Aβ 诱导的认知障碍。

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AChE/Aβ-IN-5 Chemical Structure

AChE/Aβ-IN-5 Chemical Structure

CAS No. : 181114-32-9

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AChE/Aβ-IN-5 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

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AChE BChE

  • 生物活性

生物活性

AChE/Aβ-IN-5 (compound AV-2) is a bifunctional inhibitor that targets AChE and auto-induced Aβ (Amyloid-β) aggregation. AChE/Aβ-IN-5 can significantly improve scopolamine- and Aβ-induced cognitive impairment in mice[1].

IC50 & Target

AChE[1]
分子量

380.48

Formula

C25H24N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

AChE/Aβ-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/Aβ-IN-5181114-32-9Amyloid-βCholinesterase (ChE)β-amyloid peptideAβAbetaY mazeMorris water mazecognitive impairmentInhibitorinhibitorinhibit

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