2. Cell Cycle/DNA Damage
  3. DNA Alkylator/Crosslinker
  4. Anticancer agent 11

Anticancer agent 11 是一种广谱抗癌剂，可抑制血管生成并诱导 DNA 交联。

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Anticancer agent 11 Chemical Structure

Anticancer agent 11 Chemical Structure

CAS No. : 2332936-95-3

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Anticancer agent 11 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 11 is a broad-spectrum anticancer agent that inhibits angiogenesis and induces DNA cross-links.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
786-0 IC50
0.37 μM
Compound: 19a
Cytotoxicity against human 786-0 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human 786-0 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
A549 IC50
1.55 μM
Compound: 19a
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
CCRF-CEM IC50
0.19 μM
Compound: 19a
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
CEM-VLB IC50
0.1 μM
Compound: 19a
Cytotoxicity against human CEM-VLB cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human CEM-VLB cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
EA.hy 926 IC50
2.86 μM
Compound: 19a
Cytotoxicity against human EA.hy 926 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human EA.hy 926 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
HCT-116 IC50
0.65 μM
Compound: 19a
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H1417 IC50
0.42 μM
Compound: 19a
Cytotoxicity against human NCI-H1417 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H1417 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H146 IC50
1.17 μM
Compound: 19a
Cytotoxicity against human NCI-H146 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H146 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H1650 IC50
1.2 μM
Compound: 19a
Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H1975 IC50
0.98 μM
Compound: 19a
Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H211 IC50
0.12 μM
Compound: 19a
Cytotoxicity against human NCI-H211 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H211 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H2170 IC50
3.27 μM
Compound: 19a
Cytotoxicity against human NCI-H2170 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H2170 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H226 IC50
0.67 μM
Compound: 19a
Cytotoxicity against human NCI-H226 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H226 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H460 IC50
1.02 μM
Compound: 19a
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H520 IC50
1.37 μM
Compound: 19a
Cytotoxicity against human NCI-H520 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H520 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H526 IC50
0.04 μM
Compound: 19a
Cytotoxicity against human NCI-H526 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H526 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
NCI-H82 IC50
0.31 μM
Compound: 19a
Cytotoxicity against human NCI-H82 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Cytotoxicity against human NCI-H82 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
[PMID: 34459195]
分子量

335.40

Formula

C20H21N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 11 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 112332936-95-3Anticancer agent11Anticancer agent-11DNA Alkylator/CrosslinkerInhibitorinhibitorinhibit

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