2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Conantokin G

Conantokin G 是一种 17 个氨基酸的肽，是一种有效，选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G 抑制鼠皮质神经元中 NMDA 诱发的电流，IC50 为 480 nM，具有神经保护作用。

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Custom Peptide Synthesis

Conantokin G Chemical Structure

Conantokin G Chemical Structure

CAS No. : 93438-65-4

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Other Forms of Conantokin G:

Conantokin G 相关抗体

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AMPA Receptor NMDA Receptor Kainate Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Conantokin G, a 17-amino-acid peptide, is a potent, selective and competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. Conantokin G inhibits NMDA-evoked currents in murine cortical neurons with an IC50 of 480 nM. Conantokin G has neuroprotective properties[1][2].

IC50 & Target

NMDA Receptor

 

分子量

2264.19

Formula

C88H138N26O44
CAS 号
Sequence Shortening

GE-{Gla}-{Gla}-LQ-{Gla}-NQ-{Gla}-LIR-{Gla}-KSN-NH2
结构分类
初始来源

Conus geographus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Conantokin G 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Conantokin G93438-65-4iGluRIonotropic glutamate receptorsNMDAneuroprotectivemurinecorticalneuronsInhibitorinhibitorinhibit

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目录号：
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