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  4. CYP1A1 inhibitor 8a

CYP1A1 inhibitor 8a是一种强效且选择性抑制CYP1A1酶的化合物，具有预防癌症的潜力。CYP1A1 inhibitor 8a对CYP1A1表现出超过10倍的选择性，相较于CYP1亚家族的其他酶表现出超过100倍的选择性。CYP1A1 inhibitor 8a能有效拮抗由B[a]P介导的芳香烃受体（AhR）在酵母细胞中的激活，并且保护人类细胞免受CYP1A1介导的B[a]P毒性。CYP1A1 inhibitor 8a具有作为癌症化学预防剂开发的潜力。

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CYP1A1 inhibitor 8a Chemical Structure

CYP1A1 inhibitor 8a Chemical Structure

CAS No. : 1821136-07-5

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CYP1A1 inhibitor 8a 相关抗体

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生物活性

CYP1A1 inhibitor 8a is a compound that potently and selectively inhibits the CYP1A1 enzyme and has the potential to prevent cancer. CYP1A1 inhibitor 8a exhibits more than 10-fold selectivity for CYP1A1 and more than 100-fold selectivity over other enzymes in the CYP1 subfamily. CYP1A1 inhibitor 8a can effectively antagonize B[a]P-mediated activation of the aryl hydrocarbon receptor (AhR) in yeast cells and protect human cells from CYP1A1-mediated B[a]P toxicity. CYP1A1 inhibitor 8a has the potential to be developed as a cancer chemopreventive agent[1].

分子量

299.32

Formula

C17H17NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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CYP1A1 inhibitor 8a 相关分类

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Keywords:

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