1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. FMAU

FMAU 是一种胸腺嘧啶核苷类似物。该系列的类似物对复制的 DNA 具有插入活性。它们可用于标记细胞,追踪 DNA 合成。

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FMAU Chemical Structure

FMAU Chemical Structure

CAS No. : 69256-17-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HL-60 IC50
> 1 mM
Compound: 14
Inhibition of human promyelocytic leukemic cell (HL-60) by XXT-microculture tetrazolium assay
Inhibition of human promyelocytic leukemic cell (HL-60) by XXT-microculture tetrazolium assay
[PMID: 2033590]
Vero ED50
0.018 μM
Compound: 1a
Compound was tested for antiviral activity against Herpes simplex virus-1 (Strain F) in vero cells by plaque reduction assay.
Compound was tested for antiviral activity against Herpes simplex virus-1 (Strain F) in vero cells by plaque reduction assay.
[PMID: 3001306]
Vero ED50
0.023 μM
Compound: 1a
Compound was tested for antiviral activity against Herpes simplex virus-2 (Strain G) in vero cells by plaque reduction assay.
Compound was tested for antiviral activity against Herpes simplex virus-2 (Strain G) in vero cells by plaque reduction assay.
[PMID: 3001306]
分子量

260.22

Formula

C10H13FN2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
FMAU
目录号:
HY-114247
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