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  4. FPPS-IN-2

FPPS-IN-2 (compound 4a) 是一种有效的和具有口服活性的 HFPPS 抑制剂，IC50 值为 1.108 µM。FPPS-IN-2 具有用于骨质疏松症研究的潜力。

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FPPS-IN-2 Chemical Structure

FPPS-IN-2 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

FPPS-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis[1].

IC50 & Target

IC50: 1.108 µM (HFPPS)[1]
体内研究
(In Vivo)

FPPS-IN-2 (compound 4a) (0.1, 1, 10 mg/kg; p.o.; daily for 8 weeks) 在卵巢切除大鼠中显示出抗骨质疏松功效[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 200-250 g, Female Wistar rats[1]
Dosage: 0.1, 1, 10 mg/kg
Administration: P.o.; daily for 8 weeks
Result: Increased the osteocalcin level only with the 1, and 10 mg/kg doses, reduced urinary calcium.
分子量

410.46

Formula

C24H26O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FPPS-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FPPS-IN-2Othersorally activeovariectomized ratsosteoporosisInhibitorinhibitorinhibit

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产品名称：
FPPS-IN-2
目录号：
HY-163832
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