2. Gene
  3. Calcr - calcitonin receptor Gene

Calcr - calcitonin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：降钙素受体

种属: Rattus norvegicus

基因 ID: 116506 | 基因类型: protein coding

关于 Calcr

Primary_assembly 4: 31,661,273-31,736,392 reverse strand.mRatBN7.2:CM026977.1

This gene has 2 transcripts (splice variants), 218 orthologues, 42 paralogues and is associated with 4 phenotypes. Biased expression in Kidney (RPKM 27.7), Brain (RPKM 15.8) and 1 other tissue.

功能概要

该基因编码的蛋白可启动降钙素结合活性和降钙素受体活性。参与腺苷酸环化酶调节 G 蛋白偶联受体信号通路。位于轴突和神经细胞体。该基因的人类直系同源物与骨质疏松症有关。与人类 CALCR（降钙素受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Calcitonin binding activity and Calcitonin receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in axon and neuronal cell body. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human CALCR (Calcitonin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Calcr 基因产物(2)

mRNA Protein Name
NM_053816.2 NP_446268.2 calcitonin receptor isoform 1b precursor
NM_001034015.1 NP_001029187.1 calcitonin receptor isoform 1a precursor

Calcr 蛋白结构

HRM

HRM: pfam02793 (85 - 153)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (161 - 471)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (163 - 188)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (197 - 219)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (273 - 300)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (312 - 332)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (347 - 376)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (390 - 417)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (423 - 448)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 533 a.a.
蛋白主名 其他名称

calcitonin receptor

C1A/C1B

CT-R

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01832 CALCR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01833 Calcr Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01834 Calcr Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calcr NCBI NCBI:799
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