Cd59a - CD59a antigen Gene

种属: Mus musculus

同用名: Cd59; protectin

关于 Cd59a

功能概要

Predicted to enable complement binding activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of Fibroblast Growth Factor production; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Acts upstream of or within negative regulation of activation of membrane attack complex. Located in external side of plasma membrane. Is expressed in several structures, including Meckel's cartilage; nervous system; neural retina; skeleton; and testis. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian Cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)). [provided by Alliance of Genome Resources, Apr 2022]