2. Gene
  3. LCN8 - lipocalin 8 Gene

LCN8 - lipocalin 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脂质运载蛋白 8

种属: Homo sapiens

同用名: EP17; LCN5

基因 ID: 138307 | 基因类型: protein coding

关于 LCN8

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,754,386-136,758,543 (from NCBI)

This gene has 5 transcripts (splice variants), 172 orthologues and 12 paralogues. Low expression observed in reference dataset.

功能概要

脂质运载蛋白家族的成员，如 LCN8，具有一个共同的结构，由一个 8 链反平行 β 桶组成，形成一个杯形配体结合口袋或花萼。脂质运载蛋白通常结合小的疏水性配体并将它们运输到特定细胞 (Suzuki et al., 2004 [PubMed 15363845]) 。[OMIM 提供，2009 年 8 月]

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

LCN8 基因产物(2)

mRNA Protein Name
NM_001345934.2 NP_001332863.1 epididymal-specific lipocalin-8 isoform 1 precursor
NM_178469.4 NP_848564.2 epididymal-specific lipocalin-8 isoform 2

LCN8 蛋白结构

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (11 - 131)

  • 0
  • 100
  • 152 a.a.
蛋白主名 其他名称

epididymal-specific lipocalin-8

epididymis secretory sperm binding protein

重组 LCN8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77056 LCN8 Protein, Human (HEK293, His) Q6JVE9-2/NP_848564.2 (M1-I152) ≥95%

关联疾病

疾病名称 别名
Night Blindness, Congenital Stationary, Autosomal Dominant 1

Congenital Stationary Night Blindness Autosomal Dominant 1

CSNBAD1

Rhodopsin-Related Congenital Stationary Night Blindness

Night Blindness, Congenital Stationary, Rhodopsin-Related

Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 1
Alopecia, Neurologic Defects, And Endocrinopathy Syndrome

Ane Syndrome

ANES

Alopecia-Progressive Neurological Defect-Endocrinopathy Syndrome

Alopecia-Progressive Neurological Defect-Endocrinopathy

Endocrine System Diseases
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07559 LCN8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta LCN8 VGNC VGNC:74136
Rattus norvegicus LCN8 RGD RGD:1306747
Mus musculus LCN8 MGD MGI:2135945
Bos taurus LCN8 VGNC VGNC:59344
Canis familiaris LCN8 VGNC VGNC:42613
Others LCN8 NCBI
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