2. Gene
  3. Epha7 - Eph receptor A7 Gene

Epha7 - Eph receptor A7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ebk; Ehk3; Mdk1; Cek11; Hek11

基因 ID: 13841 | 基因类型: protein coding

关于 Epha7

功能概要

Enables chemorepellent activity; growth factor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including Ephrin Receptor signaling pathway; negative regulation of nervous system development; and regulation of protein phosphorylation. Acts upstream of or within nephric duct morphogenesis; nervous system development; and positive regulation of neuron apoptotic process. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; foot bone; genitourinary system; and sensory organ. Orthologous to human EphA7 (EPH receptor A7). [provided by Alliance of Genome Resources, Apr 2022]

Epha7 基因产物(3)

mRNA Protein Name
NM_001122889.1 NP_001116361.1 ephrin type-A receptor 7 isoform 2 precursor
NM_001290434.1 NP_001277363.1 ephrin type-A receptor 7 isoform 3 precursor
NM_010141.4 NP_034271.3 ephrin type-A receptor 7 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GPI-linked ephrin receptor activity IDA
IDA: 通过直接分析推断
11089974 MGI
enables axon guidance receptor activity IMP
IMP: 通过突变表型推断
16301174 MGI
enables chemorepellent activity IDA
IDA: 通过直接分析推断
15996548 MGI
enables growth factor binding IPI
IPI: 通过物理相互作用推断
22568954 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11089974 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in brain development IMP
IMP: 通过突变表型推断
15902206 MGI
acts upstream of or within branching morphogenesis of a nerve IMP
IMP: 通过突变表型推断
15996548 MGI
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
11089974 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
24707048 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
24707048 MGI
involved in negative regulation of collateral sprouting IDA
IDA: 通过直接分析推断
19036963 MGI
involved in negative regulation of synapse assembly IDA
IDA: 通过直接分析推断
19036963 MGI
acts upstream of or within nephric duct morphogenesis IGI
IGI: 通过遗传相互作用推断
25139858 MGI
acts upstream of neuron apoptotic process IMP
IMP: 通过突变表型推断
15902206 MGI
acts upstream of or within positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
15902206 MGI
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
19036963 MGI
involved in regulation of cell-cell adhesion IDA
IDA: 通过直接分析推断
11089974 MGI
involved in regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: 通过直接分析推断
15902206 MGI
involved in regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
11089974 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
24707048 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
24707048 MGI
involved in regulation of protein autophosphorylation IDA
IDA: 通过直接分析推断
11089974 MGI
acts upstream of or within retinal ganglion cell axon guidance IMP
IMP: 通过突变表型推断
15996548 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24707048 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
24707048 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin type-A receptor 7

EPH homology kinase 3

developmental kinase 1

embryonic brain kinase

重组 Epha7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75746 EphA7 Protein, Mouse (HEK293, His) Q61772 (Q28-I556) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04431 EPHA7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epha7 NCBI NCBI:2045
Rattus norvegicus Epha7 NCBI NCBI:171287
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