2. Gene
  3. Ptgdr - prostaglandin D receptor Gene

Ptgdr - prostaglandin D receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：前列腺素 D 受体

种属: Mus musculus

同用名: DP; PGD

基因 ID: 19214 | 基因类型: protein coding

关于 Ptgdr

Chromosome 14: 45,088,692-45,096,832 reverse strand.GRCm39:CM001007.3

This gene has 1 transcript (splice variant), 117 orthologues, 7 paralogues and is associated with 18 phenotypes. Biased expression in testis adult (RPKM 1.2), CNS E18 (RPKM .5) and 14 other tissues.

功能概要

该基因编码的蛋白可启动前列腺素 D 受体活性和前列腺素 J 受体活性。作用于多个过程的上游或内部，包括腺苷代谢过程；细胞对前列腺素 D 刺激的反应；和男性的性别决定。位于质膜。以多种结构表达，包括消化系统；脑;淋巴系统腺体；生殖系统;和呼吸系统。该基因的人类直系同源物与哮喘有关。与人类 PTGDR（前列腺素 D2 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables prostaglandin D receptor activity and prostaglandin J receptor activity. Acts upstream of or within several processes, including adenosine metabolic process; cellular response to prostaglandin D stimulus; and male sex determination. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR (prostaglandin D2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgdr 基因产物(1)

mRNA Protein Name
NM_008962.4 NP_032988.3 prostaglandin D2 receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin D receptor activity IDA
IDA: 通过直接分析推断
12878180 MGI
enables prostaglandin J receptor activity IDA
IDA: 通过直接分析推断
12878180 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenosine metabolic process IMP
IMP: 通过突变表型推断
11562489 MGI
acts upstream of or within cellular response to prostaglandin D stimulus IMP
IMP: 通过突变表型推断
11562489 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
15834430 MGI
acts upstream of or within male sex determination IMP
IMP: 通过突变表型推断
16185683 MGI
acts upstream of or within sleep IMP
IMP: 通过突变表型推断
11562489 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11562489 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Ptgdr 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (15 - 330)

7tm_GPCRs

7tm_GPCRs: cd14964 (17 - 41)

7tm_GPCRs

7tm_GPCRs: cd14964 (60 - 82)

7tm_GPCRs

7tm_GPCRs: cd14964 (104 - 126)

7tm_GPCRs

7tm_GPCRs: cd14964 (149 - 165)

7tm_GPCRs

7tm_GPCRs: cd14964 (194 - 217)

7tm_GPCRs

7tm_GPCRs: cd14964 (262 - 284)

7tm_GPCRs

7tm_GPCRs: cd14964 (297 - 322)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
蛋白主名 其他名称

prostaglandin D2 receptor

PGD receptor

PGD2 receptor

prostanoid DP receptor

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11368 PTGDR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11369 Ptgdr Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11370 PTGDR Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11371 PTGDR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11372 Ptgdr2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11373 Ptgdr2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgdr NCBI NCBI:5729
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