Prmt7 - protein arginine N-methyltransferase 7 Gene

中文名称：蛋白质精氨酸 N-甲基转移酶 7

种属: Mus musculus

同用名: 4933402B05Rik

关于 Prmt7

功能概要

该基因编码的蛋白可启动组蛋白甲基转移酶活性（H4-R3 特异性）和蛋白质-精氨酸 omega-N 对称甲基转移酶活性。参与参与配子生成的 DNA 甲基化；组蛋白精氨酸甲基化；基因印记对基因表达的调控。预测位于胞质溶胶中；纤维中心;和核质。在几种结构中表达，包括大脑和视网膜核层。与人类 PRMT7（蛋白质精氨酸甲基转移酶 7）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Histone Methyltransferase activity (H4-R3 specific) and protein-arginine omega-N symmetric methyltransferase activity. Involved in DNA methylation involved in gamete generation; histone arginine methylation; and regulation of gene expression by genetic imprinting. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Is expressed in several structures, including brain and retina nuclear layer. Orthologous to human PRMT7 (protein arginine methyltransferase 7). [provided by Alliance of Genome Resources, Apr 2022]