2. Gene
  3. Epo - erythropoietin Gene

Epo - erythropoietin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24335 | 基因类型: protein coding

关于 Epo

功能概要

Predicted to enable cytokine activity; erythropoietin receptor binding activity; and protein kinase activator activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of activated T cell proliferation; and response to dexamethasone. Located in cell body and extracellular space. Used to study retinal detachment and visual epilepsy. Biomarker of cholangiocarcinoma; eye disease (multiple); transient cerebral ischemia; and vascular dementia. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Orthologous to human EPO (erythropoietin). [provided by Alliance of Genome Resources, Apr 2022]

Epo 基因产物(1)

mRNA Protein Name
NM_017001.2 NP_058697.1 erythropoietin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
19840250 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
21749867 RGD
involved in positive regulation of activated T cell proliferation IDA
IDA: 通过直接分析推断
21649646 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
21749867 RGD
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
12876482 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
22469063 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
15470751 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
21540288 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
19185286 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
15784734 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
19768476 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
19497871 RGD
involved in response to interleukin-1 IEP
IEP: 通过表达模式推断
9321887 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9321887 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
19136608 RGD
involved in response to salt stress IEP
IEP: 通过表达模式推断
16815869 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
15778925 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
9027729 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body IDA
IDA: 通过直接分析推断
17554621 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
15470751 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

erythropoietin

重组 Epo 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73040 Erythropoietin Protein, Rat (sf9, His) P29676-1 (A27-R192) ≥95%

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-12654 Molidustat Inhibitor 98.75% Phase 3
HY-17029 Epothilone B 99.93% Phase 3
Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145405 C12-200 99.91% 否
HY-13503 Epothilone A 99.75% 否
HY-W062700 STS-E412 99.72% 否
HY-N0403 2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside Inhibitor 99.78% 否
HY-136185 Atorvastatin Epoxy Tetrahydrofuran Impurity / 否
HY-141625 TRC160334 Inhibitor ≥95.0% 否
HY-141625A TRC160334 sodium Inhibitor / 否
HY-155009 PHD2-IN-1 Inhibitor / 否
HY-156526 PHD-IN-1 Inhibitor / 否
HY-161660 DS44470011 Inhibitor / 否
HY-162438 PHD2-IN-2 Inhibitor / 否
HY-163839 DS-1093a Inhibitor / 否
HY-16444 Sagopilone / 否
HY-RS04446 EPO Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W747868 Molidustat sodium Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epo NCBI NCBI:2056
Macaca fascicularis Epo NCBI NCBI:101925524
Mus musculus Epo NCBI NCBI:13856
Susscrofa domestica Epo NCBI
Macaca mulatta Epo NCBI NCBI:719294
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