Grm4 - glutamate metabotropic receptor 4 Gene

中文名称：谷氨酸代谢型受体 4

种属: Rattus norvegicus

同用名: mGluR4

关于 Grm4

功能概要

该基因编码的蛋白可启动钙依赖性蛋白结合活性和钙调蛋白结合活性。预计参与腺苷酸环化酶抑制G蛋白偶联谷氨酸受体信号通路；化学突触传递的调节；和 MAPK 级联的正调控。预计在化学突触传递和学习的上游或内部起作用。位于树突轴；突触前活动区膜；和终端按钮。与人类 GRM4（谷氨酸代谢受体 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium-dependent protein binding activity and Calmodulin binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; modulation of chemical synaptic transmission; and positive regulation of MAPK cascade. Predicted to act upstream of or within chemical synaptic transmission and learning. Located in dendritic shaft; presynaptic active zone membrane; and terminal bouton. Orthologous to human GRM4 (glutamate metabotropic receptor 4). [provided by Alliance of Genome Resources, Apr 2022]