Acat1 - acetyl-CoA acetyltransferase 1 Gene

中文名称：乙酰辅酶 A 乙酰转移酶 1

种属: Rattus norvegicus

同用名: RATACAL

关于 Acat1

功能概要

该基因编码的蛋白可启动多种功能，包括乙酰辅酶 A C-乙酰转移酶活性；辅酶 A 结合活性；和相同的蛋白质结合活性。参与多个过程，包括动物器官发育；对激素的反应；以及对饥饿的反应。位于线粒体基质中。终末期肾病和肾病综合征的生物标志物。该基因的人类直系同源物与 β-酮硫解酶缺乏症和碳水化合物代谢紊乱有关。与人类 ACAT1（乙酰辅酶 A 乙酰转移酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including acetyl-CoA C-acetyltransferase activity; coenzyme A binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; response to hormone; and response to starvation. Located in mitochondrial matrix. Biomarker of end stage renal disease and nephrotic syndrome. Human ortholog(s) of this gene implicated in beta-ketothiolase deficiency and carbohydrate metabolic disorder. Orthologous to human ACAT1 (acetyl-CoA acetyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]