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  3. Htr5a - 5-hydroxytryptamine receptor 5A Gene

Htr5a - 5-hydroxytryptamine receptor 5A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：5-羟色胺受体 5A

种属: Rattus norvegicus

同用名: MR22; 5HT5A

基因 ID: 25689 | 基因类型: protein coding

关于 Htr5a

Primary_assembly 4: 7,444,968-7,454,651 reverse strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 215 orthologues, 8 paralogues and is associated with 2 phenotypes. Restricted expression toward (RPKM 3.).

功能概要

该基因编码的蛋白可启动 G 蛋白偶联血清素受体活性。参与G蛋白偶联受体信号通路，偶联环核苷酸第二信使；海马体发育；和对雌二醇的反应。位于多种细胞成分中，包括高尔基体；核周;和粗面内质网。是突触后特化膜的组成部分。与人 HTR5A（5-羟色胺受体 5A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled serotonin receptor activity. Involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; hippocampus development; and response to estradiol. Located in several cellular components, including Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Is integral component of postsynaptic specialization membrane. Orthologous to human HTR5A (5-hydroxytryptamine receptor 5A). [provided by Alliance of Genome Resources, Apr 2022]

Htr5a 基因产物(1)

mRNA Protein Name
NM_013148.2 NP_037280.1 5-hydroxytryptamine receptor 5A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled serotonin receptor activity IMP
IMP: 通过突变表型推断
7682702 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IMP
IMP: 通过突变表型推断
10861802 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
16572590 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
17122082 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
17394137 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
15282708 RGD
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
16082681 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Htr5a 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (40 - 348)

7tm_GPCRs

7tm_GPCRs: cd14964 (42 - 66)

7tm_GPCRs

7tm_GPCRs: cd14964 (75 - 97)

7tm_GPCRs

7tm_GPCRs: cd14964 (114 - 136)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (197 - 220)

7tm_GPCRs

7tm_GPCRs: cd14964 (283 - 305)

7tm_GPCRs

7tm_GPCRs: cd14964 (316 - 341)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
蛋白主名 其他名称

5-hydroxytryptamine receptor 5A

5-HT-5A

5-HT5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

REC17

serotonin receptor 5A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06477 HTR5A Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06478 Htr5a Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06479 Htr5a Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Htr5a NCBI NCBI:3361
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